distal-less

13 examples (0.03 sec)
  • All six are homologs of the fly gene Distal-less.
  • In this case the gene Distal-less is very under-expressed, or not expressed at all, in the regions where limbs would form in other tetrapods.
  • This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene.
  • This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less (Dll) gene.
  • Ubx and abd-A repress the expression of Distal-less, Dll, a gene responsible for the development of limbs.
  • Distal-less itself, and its homologues, is involved in limb development in most of the major phyla, including vertebrates -- suggesting that it was involved in appendage growth in an early bilaterial ancestor.
  • The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6.
  • DLX is a family of homeodomain transcription factors which are related to the Drosophila distal-less (Dll) gene.
  • Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly.
  • The cause of this disease is a mutation in the DLX3 (distal-less 3) gene, which controls hair follicle differentiation and induction of bone formation.
  • Homeobox protein DLX-5 is a protein that in humans is encoded by the distal-less homeobox 5 gene, or DLX5 gene.
  • Classic examples of this are the already mentioned Distal-less gene, which is responsible for appendage formation in both tetrapods and insects, or, at a finer scale, the generation of wing patterns in the butterflies Heliconius erato and Heliconius melpomene.
  • A four base pair deletion in exon 3 is also noted in patients with TDO; deletion in two transcription factor genes DLX-3 and DLX-7 gene (distal-less gene) that occurs by a frameshift mutation, makes this gene shorter than its normal length and non-functional.