cytoplasmic region

18 examples (0.04 sec)
  • The cytoplasmic region contains four ITIMs that become phosphorylated after binding of ligand.
  • He further showed that in the unsegmented but mature egg prelocalised cytoplasmic regions can be distinguished, which later become separated from one another through the segmentation of the egg. Cited from Form and Function, by E. S. (Edward Stuart) Russell
  • However, a recent study has called into question the importance of this interaction and suggested that interaction with the cytoplasmic region of the beta-3 integrin subunit is important.
  • The N-terminal domain of this protein forms part of the cytoplasmic region of the protein, which may be the sensor domain responsible for sensing turgor pressure.
  • The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region.
  • In molecular biology, the cadherin cytoplasmic region is a conserved region found at the C-terminus of cadherin proteins.
  • The cytoplasmic regions of SNARE found on transport vesicles and target membranes interact, then a four-helix coiled coil forms.
  • All of these proteins are mosaic proteins composed of various domains and that all have a large extracellular region, often followed by either a transmembrane region and a very short cytoplasmic region or by a GPI-anchor.
  • The cytoplasmic region is highly conserved in sequence and has been shown experimentally to regulate the cell-cell binding function of the extracellular domain of E-cadherin, possibly through interaction with the cytoskeleton.
  • RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions.
  • D 1 and D 2 receptors interact primarily through discrete amino acids in the cytoplasmic regions of each receptor, with no involvement of transmembrane parts.
  • All RTKs consists of an extracellular ligand binding region, a single transmembrane helix and a cytoplasmic region (the tyrosine kinase domain).
  • This 4.1 band domain binds to the cytoplasmic region of transmembrane proteins including glycophorin C, actin and spectrin.
  • Cytoplasmic region concists of tyrosine residues conform to inhibitory ITIMs that associates with phosphataseSHP2.
  • A key determinant to the strength of the binding that it is mediated by cadherins is the juxtamembrane region (the part of the cytoplasmic region which is adjacent to the transmembrane domain) of the cadherin.
  • HCN isoforms are highly conserved in their core transmembrane regions and cyclic nucleotide binding domain (80-90% identical), but diverge in their amino- and carboxy-terminal cytoplasmic regions.
  • It was identified in the human intracellular protein termed CD2 binding protein 2 (CD2BP2), which binds to a site containing two tandem PPPGHR segments within the cytoplasmic region of CD2.
  • Cytoplasmic regions 2 and 3, and TM domains 1, 2, 4, 5, 7 and 10 are well conserved: the conserved cytoplasmic regions are believed to interact with cytoplasmic secretion factors, while the TM domains may participate in protein export.