axon pruning

8 examples (0.02 sec)
  • Hormones and trophic factors are thought to be the main extrinsic factors regulating large-scale stereotyped axon pruning.
  • EphrinB3 reverse signaling is important for axon pruning and synapse and spine formation during postnatal development of the nervous system.
  • This variation of pruning is known as large-scaled stereotyped axon pruning.
  • In all cases, the synapses are formed by a transient axon terminal, and synapse elimination is caused by the axon pruning.
  • Semaphorins have also been shown to mediate other neuronal processes besides targeting such as: apoptosis, cell migration, axon pruning, synaptic transmission, and axonal transport.
  • In neuroscience, synaptic pruning or axon pruning is the process of synapse elimination that occurs between early childhood and the onset of puberty in many mammals.
  • Because Sema3A is involved in growth cone collapse and axon pruning and repulsion, it potentially holds a causal relationship to synaptic weakening and denervation that precedes motor neuron apoptosis in ALS.
  • These Nrp-plexin and semaphorin complexes initiate cascades that regulate diverse processes such as axon pruning and repulsion, dendritic attraction and branching, regulation of cell migration, vascular remodeling, and growth cone collapse.