axon growth

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  • During development of the central nervous system, FGFs play important roles in neurogenesis, axon growth, and differentiation.
  • Researchers have been using neuromorphological techniques to not only study the damage but also ways to regenerate the damage nerve through ways like axon growth stimulation.
  • Human axon growth rates can reach 2 mm/day in small nerves and 5 mm/day in large nerves.
  • Observations of axon growth during the early embryonic period have led to conclusions that axons are actively guided to specific locations.
  • In the later stages of regeneration the remaining endoneurial tube directs axon growth back to the correct targets.
  • Guidepost cells are cells which assist in the subcellular organization of both neuron axon growth and migration.
  • Ennui is very important in nerve-dependent acetylcholine clustering and the stability of axon growth.
  • His current research investigates the genes regulating Lozenge and subsequently what Lozenge specifically regulates during axon growth and guidance.
  • Infusion of decorin into experimental rodent spinal cord injuries has been shown to suppress scar formation and promote axon growth.
  • The filopodia are bound by membrane which contains receptors and cell adhesion molecules that are important for axon growth and guidance.
  • Fzd3 controls axon growth and guidance in the mouse nervous system, and migration of neural crest cells.
  • Other possibilities for synthetic materials are conducting polymers and polymers biologically modified to promote cell axon growth and maintain the axon channel.
  • Currently, neurotrophic factors are being intensely studied for use in bioartificial nerve conduits because they are necessary in vivo for directing axon growth and regeneration.
  • This suggests that other cues other than those from pioneer axons play a role in guiding follower axon growth, and that pioneer axons may play different roles in different parts of neuronal development.
  • Studies have shown that when CSPGs inhibit axon growth in the glial scar, the ROCK pathway is activated.
  • The binding of Slit to any member of the Roundabout receptor family results in axon repelling through changes in the axon growth cone.
  • CSPGs are the main axon growth inhibitory molecules in the glial scar that play a role in the failure of the axon to regenerate after injury.
  • Laminin is a component of the extracellular matrix that is able to promote neuron attachment and differentiation, in addition to axon growth guidance.
  • In rats a marginal iron deficiency that does not cause anemia disrupted axon growth in the auditory nerve affecting auditory brainstem latency without major changes in myelination.
  • In addition to axon growth cones, the model organism Dictyostelium discoideum has been instrumental in determining the mechanisms that mediate chemorepulsion and immunorepulsion.
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